Network predictive diagnostics for cancer immunotherapies and target discovery
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Network predictive diagnostics
for cancer immunotherapies and target discovery

Mission

Leverage our ability to delineate the immune - tumor - stroma communication networks to identify patients that are likely to respond to immunotherapy and to discover new targets and drug combinations to treat those who do not.

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From inter-cellular communication networks to predictive diagnostics and target discovery

Individual patients’ inter-cellular communication network

Non-responder
Non-responder
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responder
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responder
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responder

Response prediction based on classification

according to network patterns

responder
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Non-responder and responder
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Non-responder

Responders

Non-Responders

Biomarker Identification

Discovery of effective new drug combinations and new targets

Microscope

What We Do

Pyxis Diagnostics develops a novel computational biology platform that aims to predict patients' response to Immuno-Oncology treatments and identify potential new drug combinations disrupting resistance in non-responding patients.

Robotic Lab Assistant

How we Do It

By comparing cellular network patterns between responders and non-responders, Pyxis identifies network patterns associated with response (i.e. predictive biomarkers) and lack of response. Suppressive network pattern associated with immune-resistance mechanisms are used to identify new drugs or drug combinations to disrupt these suppressive network features.